Bone Research(2024年03期)
骨研究(英文版)

目 錄

• Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease
• Ageing-related bone and immunity changes: insights into the complex interplay between the skeleton and the immune system
• Bone targeted nano-drug and nano-delivery
• Metabolic reprogramming in skeletal cell differentiation
• Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo-CCL3 signaling
• Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor
• FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development
• PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging
• Caspase-8 promotes scramblase-mediated phosphatidylserine exposure and fusion of osteoclast precursors
• PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function
• Induction of osteoblast apoptosis stimulates macrophage efferocytosis and paradoxical bone formation
• Coactivator-independent vitamin D receptor signaling causes severe rickets in mice, that is not prevented by a diet high in calcium, phosphate, and lactose
• Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice
• Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta
• SREBP2 restricts osteoclast differentiation and activity by regulating IRF7 and limits inflammatory bone erosion
• The HOXC10/NOD1/ERK axis drives osteolytic bone metastasis of pan-KRAS-mutant lung cancer
• Osteoclasts control endochondral ossification via regulating acetyl-CoA availability
• Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects